Chen Qiong, Zhu Qinghua, Min Hua, Liu Zhouying
[Purpose/Signficance] In order to explore the interdisciplinary rule more accurately,the study constructs a framework to recognize the interdisciplinary features based on domain topics,which helps to identify interdisciplinary topics,interdisciplinary situation and interdisciplinary structure.[Method/Process] 45546 articles in the field of medical informatics in WOS database from 2000—2020 were used for empirical research.Firstly,domain topics were divided based on LDA topic model.Then,Div index was introduced to compare and analyze the interdisciplinary situation.Finally,the disciplinary edge-core subgroup structure was analysed based on co-occurrence network and betweeness centrality.[Result/Conclusion] There are nine sub topics divided,including heart signal sensing system,electronic health technology,electronic medical record system,health app and use behavior,medical care electronic system,randomized treatment experiment,image segmentation and clustering,feature recognition based on machine learning,and cancer treatment risk assessment.Among them,the interdisciplinary degree of the first five subjects shows a fluctuating upward trend in recent five years;In terms of discipline structure,engineering and computer science are the core subjects with deep interdisciplinary degree.This study is helpful for scientific research administrations and researchers to formulate relevant policies,optimize resource allocation,and identify the frontier of disciplines.[Limitations] Due to the incomplete citation information of early journals,the accuracy of interdisciplinary degree calculation would be affected to a certain extent.